Yankees vs Orioles Picks & Odds (July 22)

Yankees vs Orioles Picks & Odds (July 22)

New York Yankees starting pitcher Jameson Taillon delivering to home plate

Jul 10, 2022; Boston, Massachusetts, USA; New York Yankees starting pitcher Jameson Taillon (50) throws a pitch during the first inning against the Boston Red Sox at Fenway Park. Mandatory Credit: Paul Rutherford-USA TODAY Sports

The Yankees are -160 road favorites over the Orioles on Friday night
Jameson Taillon (10-2, 3.86) will pitch for New York against Tyler Wells (7-5, 3.38)
A look at the odds and matchups can be found below with a prediction

The top team in the American League East plays the bottom one when the New York Yankees visit the Baltimore Orioles at 7:05 p.m. ET Friday at Oriole Park at Camden Yards.

The Yankees (64-30/27-18 road) came out of the All-Star break Thursday and were swept in a doubleheader by the Astros in Houston, losing 3-2 and 7-5. New York has the best record in the major leagues but has lost four of its last six games and seven of 10.

The Orioles (46-46/25-17 home) were off Thursday. They lost two of three games to end the first half, though that came on the heels of a 10-game winning streak

Yankees vs Orioles Odds

New York Yankees
-1.5 (-105)
Over 9 (-110)
Baltimore Orioles
+1.5 (-115)
Under 9 (-110)

Odds as of July 21st at BetMGM.



The Yankees are -160 favorites in a game that will be streamed on Amazon Prime, giving them an expected win probability of 61.54%. At +400 in the World Series odds, New York is the co-favorite with the Los Angeles Dodgers, while the Orioles’ odds are +30000.

It figures to be a hot night in Baltimore with the weather forecast calling a first pitch temperature of 90 degrees and a low of 76, mostly clear and southwest wind at 3-7 mph.

Yankees vs Orioles Probable Pitchers

Jameson Taillon (10-2, 3.86) is scheduled to start for the Yankees against Tyler Wells (7-5, 3.38). Taillon, who has +8000 AL Cy Young Award odds, will be pitching on five days of rest and Wells on six.

Taillon vs Wells


Since taking a loss and no-decision in first two outings of the season, Taillon has gone 10-1 with a 3.87 ERA in 16 starts. However, he is 1-1 with a 6.61 ERA in three starts in July.

Taillon did pitch well his last out when he limited the visiting Boston Red Sox to one run on two hits in six innings last Saturday for the win. He struck out five and walked none.

Jameson Taillon earned his 10th win of the season, retiring the last 17 batters he faced against Boston. #YANKSonYES pic.twitter.com/5zxRqW4Uw2

— YES Network (@YESNetwork) July 17, 2022

This will be Taillon’s sixth career start against the Orioles, and he is 1-0 with a 3.91 ERA against them. He is 1-0 with a 4.66 ERA in two games at Camden Yards.

Taillon has a 4-1 record on the road this season and a 4.33 ERA in eight starts. He is 6-2 with a 4.26 ERA in 12 starts at night. The Yankees are 14-4 when Taillon pitches.

Wells had a six-game winning streak ended by the Tampa Bay Rays last Friday in St. Petersburg.

He pitched 5.2 innings and allowed three runs and six hits with six strikeouts and two walks. In his three starts in July, Wells has gone 1-1 with a 4.02 ERA.

Against the Yankees, Wells has an 0-2 career mark with a 3.32 ERA in nine games (three starts).

Tyler Wells, Nasty 87mph Changeup. ? pic.twitter.com/vipMDfM5YQ

— Rob Friedman (@PitchingNinja) July 16, 2022

Wells has pitched well in Baltimore this season with a 2-0 record and 2.76 ERA in seven starts. In 10 starts at night, he is 3-2 with a 2.74 ERA. The Orioles are 10-8 when Wells takes the mound.

Batting Average vs Starting Pitchers

Yankees Batters
Batting Average vs Tyler Wells
Aaron Judge
Kyle Higashioka
Jose Trevino
Giancarlo Stanton
Gleyber Torres
Aaron Hicks
Anthony Rizzo
Joey Gallo
Isiah Kiner-Falefa
Josh Donaldson
Marwin Gonzalez
DJ LeMahieu
Orioles Batters
Batting Average vs Jameson Taillon
Tyler Nevin
Austin Hays
Cedric Mullins
Jorge Mateo
Ryan McKenna
Ramon Urias
Trey Mancini
Ryan Mountcastle
Rougned Odor
Anthony Santander

The Yankees’ Aaron Judge is 4 for 11 (.364) with one home run off Wells. However, Anthony Rizzo, Joey Gallo, Isiah Kiner-Falefa, Josh Donaldson, Marwin Gonzalez and DJ LeMahieu are hitless in 31 at-bats combined against the big right-hander.

The Orioles’ Austin Hays is 6 for 11 (.545) against Taillon with two doubles while Cedric Mullins has gone 4 for 11 (.364) with two homers. Anthony Santander, conversely, is 1 for 10 (.100).

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Yankees vs Orioles Betting Outlook

Judge hit a three-run home run, his MLB-leading 34th, in the ninth inning of the second game of Thursday’s twinbill. Yet it wasn’t enough to keep the Yankees from losing 7-5 as the Astros completed the sweep.

#AllRise for Homer No. 34 pic.twitter.com/c95MqPtToe

— New York Yankees (@Yankees) July 22, 2022

Gleyber Torres also went deep as he finished with two hits and two RBIs. Donaldson added two hits.

The Yankees lost the opener 3-2. Astros rookie J.J. Matijevic walked it off in the ninth inning with a pinch-hit RBI single with two outs off Michael King.

Aaron Hicks had two of New York’s five hits.

The Yankees are 9-4 this season against the Orioles and have won four of seven games in Baltimore. Jose Trevino has gone 9 for 21 (.429) for New York with two doubles and two home runs and Judge is hitting .333 (15 for 45) with two doubles and six longballs.

Trevino and Yankees batterymate Nestor Cortes Jr. were two of the stars of Fox’s telecast of the All-Star Game on Tuesday.

This is awesome.

Jose Trevino & Nestor Cortes are mic’d up with each other and talking us through the inning pitch-by-pitch ?

(via @MLBONFOX) pic.twitter.com/HnkG0SLz1q

— B/R Walk-Off (@BRWalkoff) July 20, 2022

Since the start of the 2017 season, the Yankees hold a commanding 68-31 in the series.

Yankees vs Orioles Last 10 Games

Home Team
Away Team
NYY, 2-0
NYY, 7-6
BAL, 6-4
BAL, 9-6
NYY, 3-2
NYY, 5-4
NYY, 6-2
NYY, 10-5
NYY, 5-2
NYY, 12-8

Yankees vs Orioles Prediction

Taillon finished the first half on a good note following some struggles. Yet Wells is an intriguing underdog play, especially with so many Yankees having had trouble against him.

Pick: Orioles ML (+135) 


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John Perrotto

Sports Writer

Sports Writer

John Perrotto has been covering and writing about sports for various outlets for over 40 years. His work has appeared in the likes of USA TODAY, ESPN.com, SI.com, Forbes.com, The Associated Press, Baseball Digest, and more. John is based out of Beaver Falls, PA.


John Perrotto has been covering and writing about sports for various outlets for over 40 years. His work has appeared in the likes of USA TODAY, ESPN.com, SI.com, Forbes.com, The Associated Press, Baseball Digest, and more. John is based out of Beaver Falls, PA.

Author: Jesse Smith